KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHGDH
All Species:
26.36
Human Site:
T480
Identified Species:
41.43
UniProt:
O43175
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43175
NP_006614.2
533
56651
T480
S
D
P
A
M
L
P
T
M
I
G
L
L
A
E
Chimpanzee
Pan troglodytes
A5A6P1
533
56644
T480
S
D
P
A
M
P
P
T
M
M
G
L
L
A
E
Rhesus Macaque
Macaca mulatta
XP_001114128
533
56466
T480
S
D
P
A
M
L
P
T
M
I
G
L
L
A
E
Dog
Lupus familis
XP_849835
533
56527
T480
S
P
P
E
M
L
P
T
M
I
G
L
L
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61753
533
56567
T480
S
D
P
G
M
L
P
T
M
I
G
L
L
A
E
Rat
Rattus norvegicus
O08651
533
56475
T480
S
D
P
V
M
L
P
T
M
I
G
L
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515318
533
55943
V480
L
D
S
L
L
L
P
V
L
I
G
L
L
A
Q
Chicken
Gallus gallus
XP_422226
525
55022
T472
S
E
T
N
A
L
P
T
L
T
G
L
L
G
K
Frog
Xenopus laevis
NP_001091250
509
53841
L456
T
L
H
G
T
L
I
L
W
E
G
S
A
P
L
Zebra Danio
Brachydanio rerio
NP_955871
527
55379
S474
C
S
T
E
F
L
S
S
I
T
G
V
L
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609496
332
35216
K280
K
A
L
I
S
H
P
K
V
V
A
T
P
H
L
Honey Bee
Apis mellifera
XP_001121753
478
51893
D424
S
D
G
I
I
L
G
D
F
I
S
L
Y
Q
T
Nematode Worm
Caenorhab. elegans
NP_496868
322
34673
R270
E
Q
E
P
P
T
F
R
E
L
I
D
H
P
L
Sea Urchin
Strong. purpuratus
XP_001203904
493
51557
A440
Q
N
A
A
A
A
L
A
A
V
A
S
G
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04130
624
66436
Q566
D
Q
P
G
M
I
G
Q
V
G
N
I
L
G
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.8
92.5
N.A.
94.5
94.1
N.A.
82.5
67.5
56.2
60.7
N.A.
35
45
32.6
46.3
Protein Similarity:
100
99.6
99.2
96
N.A.
97
97.1
N.A.
90.2
80.1
71.6
75.9
N.A.
48.2
61.9
45.5
61.5
P-Site Identity:
100
86.6
100
86.6
N.A.
93.3
93.3
N.A.
53.3
46.6
13.3
26.6
N.A.
6.6
33.3
0
6.6
P-Site Similarity:
100
93.3
100
86.6
N.A.
93.3
93.3
N.A.
73.3
66.6
20
46.6
N.A.
20
40
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
27
14
7
0
7
7
0
14
0
7
54
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
47
0
0
0
0
0
7
0
0
0
7
0
0
0
% D
% Glu:
7
7
7
14
0
0
0
0
7
7
0
0
0
0
47
% E
% Phe:
0
0
0
0
7
0
7
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
7
20
0
0
14
0
0
7
67
0
7
14
7
% G
% His:
0
0
7
0
0
7
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
0
0
14
7
7
7
0
7
47
7
7
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% K
% Leu:
7
7
7
7
7
67
7
7
14
7
0
60
67
7
20
% L
% Met:
0
0
0
0
47
0
0
0
40
7
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
7
47
7
7
7
60
0
0
0
0
0
7
14
0
% P
% Gln:
7
14
0
0
0
0
0
7
0
0
0
0
0
7
7
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
54
7
7
0
7
0
7
7
0
0
7
14
0
0
0
% S
% Thr:
7
0
14
0
7
7
0
47
0
14
0
7
0
0
14
% T
% Val:
0
0
0
7
0
0
0
7
14
14
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _